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Talk of the lab
Joshua joins the lab!
Alex and Cathy's Paper is published in JITC!
Congratulations to Alex and Cathy for their paper in The Journal for ImmunoTherapy of Cancer! This work shows stimulation of both CAR molecules in a CD19xCD22 bicistronic CAR construct impacts downstream signaling events within the CAR T-cell and subsequently drives a more efficacious in vivo response with evidence of decreased exhaustion in persisting cells.
Taylor joins the Lab!
Angie is a PhD Candidate!
Congrats to Angie on becoming a PhD candidate! A major milestone and well deserved, excited for what’s ahead! 🎉🧬
Thank you to the V Foundation!
The Kohler Lab thanks the V Foundation for support through the Translational Grant, which funds our work on the development and testing of out novel CAR T cells against human and canine osteosarcoma.
Angie gives her first Research in Progress talk!
Angie meets Jin!!!
Angie celebrated passing comps by flying to New York to meet BTS Jin!
Cancer Center highlights the ALA-CART!
Cathy's paper is published in Cancer Cell!
This work from the Kohler Lab introduces a novel CAR T cell platform, ALA-CART (Adjunctive LAT-Activating CAR-T cells), designed to overcome a signaling deficiency in LAT observed in conventional CAR T cells. By restoring LAT signaling, ALA-CART cells exhibit enhanced antigen sensitivity, leading to improved efficacy and long-term persistence.
Haley and Cathy receive awards at the 2024 Cancer Center Retreat!
Congratulations to Haley for presenting her work on AML CAR T cells, and to Cathy for sharing her research on ALA-CART cells. Great work representing the lab!
Angie joins the Lab!
Taylor Swift Concert!!!
The Kohler Lab Swifities attend the concert of a lifetime!
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