Publications
Increased NFAT activity with dual CAR stimulation in CD19xCD22 CAR T-cells is associated with decreased exhaustion and improved survival
Alexander W Rankin, Catherine Pham-Danis, Amanda J Novak, Etienne Danis, Terry J Fry, M. Eric Kohler
J Immunother Cancer (2025)
Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia
Catherine Pham-Danis, Amanda J Novak, Etienne Danis, Samantha M. McClellan, Lillie Leach, Michael C. Yarnell, Christopher C. Ebmeier, Sarah K. Tasian, M. Eric Kohler
Cancer Cell (2025)
Deleting the mitochondrial respiration negative regulator MCJ enhances the efficacy of CD8+ T cell adoptive therapies in pre-clinical studies
Meng-Han Wu, Felipe Valenca-Pereira, Francesca Cendali, Emily L Giddings, Catherine Pham-Danis, Michael C Yarnell, Amanda J Novak, Tonya M Brunetti, Scott B Thompson, Jorge Henao-Mejia, Richard A Flavell, Angelo D'Allesandro, M Eric Kohler, Mercedes Rincon
Nature Communications (2024)
TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearance
Yinmeng Yang, M Eric Kohler, Christopher D Chien, Christopher T Sauter, Elad Jacoby, Chunhua Yan, Ying Hu, Kelsey Washington, Haiying Qin, Terry J Fry
Science Translational Medicine (2020)
