Publications
Increased NFAT activity with dual CAR stimulation in CD19xCD22 CAR T-cells is associated with decreased exhaustion and improved survival
Alexander W Rankin, Catherine Pham-Danis, Amanda J Novak, Etienne Danis, Terry J Fry, M. Eric Kohler
J Immunother Cancer (2025)
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Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia
Catherine Pham-Danis, Amanda J Novak, Etienne Danis, Samantha M. McClellan, Lillie Leach, Michael C. Yarnell, Christopher C. Ebmeier, Sarah K. Tasian, M. Eric Kohler
Cancer Cell (2025)
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Deleting the mitochondrial respiration negative regulator MCJ enhances the efficacy of CD8+ T cell adoptive therapies in pre-clinical studies
Meng-Han Wu, Felipe Valenca-Pereira, Francesca Cendali, Emily L Giddings, Catherine Pham-Danis, Michael C Yarnell, Amanda J Novak, Tonya M Brunetti, Scott B Thompson, Jorge Henao-Mejia, Richard A Flavell, Angelo D'Allesandro, M Eric Kohler, Mercedes Rincon
Nature Communications (2024)
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TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearance
Yinmeng Yang, M Eric Kohler, Christopher D Chien, Christopher T Sauter, Elad Jacoby, Chunhua Yan, Ying Hu, Kelsey Washington, Haiying Qin, Terry J Fry
Science Translational Medicine (2020)
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